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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP8A1 All Species: 31.82
Human Site: Y1122 Identified Species: 58.33
UniProt: Q9Y2Q0 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2Q0 NP_006086.1 1164 131369 Y1122 K K N H V N L Y R S E S L Q Q
Chimpanzee Pan troglodytes XP_001150768 1164 131363 Y1122 K K N H V N L Y R S E S L Q Q
Rhesus Macaque Macaca mulatta XP_001099138 1164 131392 Y1122 K K N H V N L Y R S E S L Q Q
Dog Lupus familis XP_849357 1158 131123 Y1116 K K N H V N L Y R S E S L Q Q
Cat Felis silvestris
Mouse Mus musculus P70704 1149 129748 Y1107 K K N H V N L Y R S E S L Q Q
Rat Rattus norvegicus XP_223390 1134 128100 Y1092 K K N H V N L Y R S E S L Q Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518853 932 104820 Y890 K K N H M N L Y R S E S L Q Q
Chicken Gallus gallus XP_420729 1223 137907 Y1181 K K N H V N L Y R S D S L Q Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002666697 916 102033 A875 N S S D Y S I A Q F S Y L E K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001137649 1324 149578 N1282 N V F T R R A N T R V E T D L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001200260 1167 132097 R1117 K R S P S S A R H L A E E E G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9XIE6 1213 137734 H1169 L P R E L S K H T G F A F D S
Baker's Yeast Sacchar. cerevisiae P39524 1355 153826 F1312 Q D A S A N P F N D N N G L G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.8 96.9 N.A. 95.8 94.5 N.A. 74.4 88.5 N.A. 53.8 N.A. 50.9 N.A. N.A. 57.6
Protein Similarity: 100 100 100 98 N.A. 97.7 96.3 N.A. 76.9 92.4 N.A. 63.4 N.A. 65.4 N.A. N.A. 74.8
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 93.3 93.3 N.A. 6.6 N.A. 0 N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 N.A. 46.6 N.A. 0 N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. 39.2 39.9 N.A.
Protein Similarity: N.A. N.A. N.A. 58.6 57.6 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 8 0 16 8 0 0 8 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 8 0 0 0 0 0 8 8 0 0 16 0 % D
% Glu: 0 0 0 8 0 0 0 0 0 0 54 16 8 16 0 % E
% Phe: 0 0 8 0 0 0 0 8 0 8 8 0 8 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 16 % G
% His: 0 0 0 62 0 0 0 8 8 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % I
% Lys: 70 62 0 0 0 0 8 0 0 0 0 0 0 0 8 % K
% Leu: 8 0 0 0 8 0 62 0 0 8 0 0 70 8 8 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 16 0 62 0 0 70 0 8 8 0 8 8 0 0 0 % N
% Pro: 0 8 0 8 0 0 8 0 0 0 0 0 0 0 0 % P
% Gln: 8 0 0 0 0 0 0 0 8 0 0 0 0 62 62 % Q
% Arg: 0 8 8 0 8 8 0 8 62 8 0 0 0 0 0 % R
% Ser: 0 8 16 8 8 24 0 0 0 62 8 62 0 0 8 % S
% Thr: 0 0 0 8 0 0 0 0 16 0 0 0 8 0 0 % T
% Val: 0 8 0 0 54 0 0 0 0 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 62 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _